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KMID : 1132720110090010005
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Genomics & Informatics
2011 Volume.9 No. 1 p.5 ~ p.11
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Recent Progresses in the Linguistic Modeling of Biological Sequences Based on Formal Language Theory
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Park Hyun-Seok
Galbadrakh Bulgan
Kim Young-Mi
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Abstract
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Treating genomes just as languages raises the possibility of producing concise generalizations about information in biological sequences. Grammars used in this way would constitute a model of underlying biological processes or structures, and that grammars may, in fact, serve as an appropriate tool for theory formation. The increasing number of biological sequences that have been yielded further highlights a growing need for developing grammatical systems in bioinformatics. The intent of this review is therefore to list some bibliographic references regarding the recent progresses in the field of grammatical modeling of biological sequences. This review will also contain some sections to briefly introduce basic knowledge about formal language theory, such as the Chomsky hierarchy, for non-experts in computational linguistics, and to provide some helpful pointers to start a deeper investigation into this field.
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KEYWORD
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natural language processing, Chomsky hierarchy, bioinformatics, formal language theory
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